From IIT Madras
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PhD & Post Docs
Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal
- Arun Maji, Corinne P. Soutar, Jiabao Zhang, Agnieszka Lewandowska, Brice E. Uno, Su Yan, Yogesh Shelke, Ganesh Murhade, Evgeny Nimerovsky, Collin G. Borcik, Andres S. Arango, Justin D. Lange, Jonnathan P. Marin-Toledo, Yinghuan Lyu, Keith L. Bailey, Patrick J. Roady, Jordan T. Holler, Anuj Khandelwal, Anna M. SantaMaria, Hiram Sanchez, Praveen R. Juvvadi, Gina Johns, Michael J. Hageman, Joanna Krise, Teclegiorgis Gebremariam, Eman G. Youssef, Ken Bartizal, Kieren A. Marr, William J. Steinbach, Ashraf S. Ibrahim, Thomas F. Patterson, Nathan P. Wiederhold, David R. Andes, Taras V. Pogorelov, Charles D. Schwieters, Timothy M. Fan, Chad M.Rienstra* & Martin D. Burke*
- Nature, 623, 2023, 1079–1085
- October 4, 2023
A unified strategy for the total syntheses of eribulin and a macrolactam analogue of halichondrin B
- K. C. Nicolaou,* Saiyong Pan, Yogesh Shelke, Stephan Rigol, Ruiyang Bao, Dipendu Das, and Qiuji Ye
- Proc. Natl. Acad. Sci. U.S.A., 2022, 119, e2208938119
- June 20, 2022
A Highly Convergent Total Synthesis of Norhalichondrin B
- K. C. Nicolaou,* Saiyong Pan, Yogesh Shelke,† Qiuji Ye,† Dipendu Das, and Stephan Rigol
- J. Am. Chem. Soc. 2021, 143, 20970–20979
- December 1, 2021
A reverse approach to the total synthesis of halichondrin B
- K. C. Nicolaou,* Saiyong Pan, Yogesh Shelke, Dipendu Das, Qiuji Ye, Yong Lu, Susanta Sau, Ruiyang Bao, Stephan Rigol
- J. Am. Chem. Soc. 2021, 143, 9267–9276
- June 9, 2021
Recent advances in the synthesis of pyrrolo[1,2-a]indoles and their derivatives
- Yogesh G. Shelke*, Pankaj E. Hande and Santosh J. Gharpure*
- Org. Biomol. Chem. 2021, 19, 7544–7574
- July 30, 2021
Recent Advances in Small Molecule-Based Intracellular pH Probes
- Pankaj E. Hande, Yogesh G. Shelke, Anindya Datta*, Santosh J. Gharpure*
- ChemBioChem 2022, 23, e202100448
- October 25, 2021
Design, Synthesis, and Biological Investigation of Epothilone B Analogues Featuring Lactone, Lactam, and Carbocyclic Macrocycles, Epoxide, Aziridine, and 1,1 Difluorocyclopropane and Other Fluorine Residues
- K. C. Nicolaou,* Yogesh G. Shelke, Balu D. Dherange, Aaron Kempema, Baiwei Lin, Christine Gu, Joseph Sandoval, Mikhail Hammond, Monette Aujay, and Julia Gavrilyuk
- J. Org. Chem. 2020, 85, 2865–2917
- February 17, 2020
Cascade Radical Cyclization on Alkynyl Vinylogous Carbonates for the Divergent Synthesis of Tetrasubstituted Furans and Dihydrofurans
- Santosh J. Gharpure*, Padmaja, V. Prasath, Yogesh G. Shelke
- Org. Lett. 2019, 21, 223−227
- December 24, 2018
Homogeneous Catalysis: A Powerful Technology for the Modification of Important Biomolecules
- Yogesh G. Shelke, Afsana Yashmeen, Aniket VA Gholap, Santosh J. Gharpure*, Anant R. Kapdi
- Chem. Asian J. 2018, 13, 2991−3013
- July 31, 2018
Lewis Acid Mediated Cascade Friedel−Crafts/Alkyne Indol-2-yl Cation Cyclization/Vinyl Cation Trapping for the Synthesis of N‑Fused Indole Derivatives
- Santosh J. Gharpure*, Yogesh G. Shelke
- Org. Lett. 2017, 19, 5406−5409
- September 22, 2017
Cascade Radical Cyclization of N-Propargylindoles: Substituents Dictate Stereoselective Formation of N‑Fused Indolines versus Indoles
- Santosh J. Gharpure*, Yogesh G. Shelke
- Org. Lett. 2017, 19, 5022−5025
- September 13, 2017
Metal-free Hydroalkoxylation-Formal [4+2] Cycloaddition Cascade for the Synthesis of Ketals
- Santosh J. Gharpure*, Santosh K. Nanda, Padmaja, Yogesh G. Shelke
- Chem.–Eur. J. 2017, 23, 10007–10012
- May 18, 2017
Lewis Acid Promoted Oxonium Ion Driven Carboamination of Alkynes for the Synthesis of 4-Alkoxy Quinolines
- Santosh J. Gharpure*, Santosh K. Nanda, Priyanka A. Adate, Yogesh G. Shelke
- J. Org. Chem. 2017, 82, 2067−2080
- January 20, 2017
Counter-Ion-Dependent Alkyne Iminium Ion Cyclization for Divergent Synthesis of N-Fused Indolylidine, Indole, and Indoline Derivatives Promoted by the Lewis/Brønsted Acid
- Santosh J. Gharpure*, Yogesh G. Shelke, Dasari Praveen Kumar
- Org. Lett. 2015, 17, 1926−1929
- March 27, 2015
Synthesis of Isochromene Derivatives Using an Intramolecular Benzylic C(sp3)–C(sp2) Bond Forming Heck Reaction on Vinylogous Carbonates
- Santosh J. Gharpure*, Yogesh G. Shelke, S Raja Bhushan Reddy
- RSC Adv. 2014, 4, 46962−46965
- September 12, 2014
Patents
Rnai oligonucleotide conjugates
- Quiroz, J. P.; Ding, S.; Shelke, Y.; Xiao, X.-Y.; Kolakowski, R. V.; Anzahaee, M. Y.
- WO 2025/054459 A1
- March 13th, 2025
A Reverse Approach to the Total Synthesis of Eribulin
- Nicolaou, K. C.; Pan, S.; Shelke, Y.; Ye, Q.; Yang, T.
- xx 2025/xxxxxx
- xxxx, 2025
One Pot Process for Synthesizing Functionalized Quinolines via Metal-Free, Oxonium Ion Driven Carboamination of Alkynes
- Gharpure, S. J.; Nanda, S. K.; Adate, P. A.; Shelke, Y. G.
- Indian Patent, Patent no. 434013
- June 06, 2023